1. Migraine in LATVIA 2007-2008 Prepared by Indra Sakne-Sokolovska Product manager Tallin 30. may

2. Pharmaceutical Market (MAT/4/2008) Total market: 220 mlj.€,+26% Triptans market: 205 th. €, +29%; +89% in DOT Number of doctors Number of GPs 1500 Number of neurologists 200 Number of pharmacies 800 Population: 2,3 M

3. Triptans market by molecules in DOT MAT/4/2008

4. Anti migrenics market by products in DOT [€]

5. Available price for patients Main Cinie activities 2007-2008 NAMEDOSAGEPRICE IN PHARMACY (euro) PRICE PER TABLET (euro) Imigran 50mg x 2 tbl. FDT Nasal spray 12.80 6.40 12.80 Sumatriptan Sandoz 50mg x 2 tbl. 100mg x 2 tbl. 11.12 20.51 5.56 10.26 Zomig 2.5mg x 3 tbl.26.548.85 Relpax 40mg x 2 tbl.12.756.38 CINIE 50mg x 2 tbl. 50mg x 6 tbl. 100mg x 2 tbl. 100mg x 6 tbl. 6.77 15.78 11.31 22.89 3.39 2.63 5.66 3.82

6. Good cooperation with pain (headache) association: -Together we organized headache conference; -Consultations and help with patients materials & home page; Education: small seminars for GPs and neurologists; Migraine days Advertisement in medical magazines PR activities: - home page www.migrena-help.lvwww.migrena-help.lv - articles about migraine - migraine dairies for patients Main Cinie activities 2007-2008

7. Thank you for your attention!