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Structures of Lung Cancer-Derived EGFR Mutants and Inhibitor Complexes: Mechanism of Activation and Insights into Differential Inhibitor Sensitivity Cai-Hong.

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Presentation on theme: "Structures of Lung Cancer-Derived EGFR Mutants and Inhibitor Complexes: Mechanism of Activation and Insights into Differential Inhibitor Sensitivity Cai-Hong."— Presentation transcript:

1 Structures of Lung Cancer-Derived EGFR Mutants and Inhibitor Complexes: Mechanism of Activation and Insights into Differential Inhibitor Sensitivity Cai-Hong Yun, Titus J. Boggon, Yiqun Li, Michele S. Woo, Heidi Greulich, Matthew Meyerson, Michael J. Eck Cancer Cell Volume 11, Issue 3, Pages 217-227 (March 2007) DOI: 10.1016/j.ccr.2006.12.017 Copyright © 2007 Elsevier Inc. Terms and Conditions Terms and Conditions

2 Figure 1 Cancer Cell 2007 11, 217-227DOI: (10.1016/j.ccr.2006.12.017) Copyright © 2007 Elsevier Inc. Terms and Conditions Terms and Conditions

3 Figure 2 Cancer Cell 2007 11, 217-227DOI: (10.1016/j.ccr.2006.12.017) Copyright © 2007 Elsevier Inc. Terms and Conditions Terms and Conditions

4 Figure 3 Cancer Cell 2007 11, 217-227DOI: (10.1016/j.ccr.2006.12.017) Copyright © 2007 Elsevier Inc. Terms and Conditions Terms and Conditions

5 Figure 4 Cancer Cell 2007 11, 217-227DOI: (10.1016/j.ccr.2006.12.017) Copyright © 2007 Elsevier Inc. Terms and Conditions Terms and Conditions

6 Figure 5 Cancer Cell 2007 11, 217-227DOI: (10.1016/j.ccr.2006.12.017) Copyright © 2007 Elsevier Inc. Terms and Conditions Terms and Conditions

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