1. Division of Comparative Medicine (DCM) Medical Sciences Building (MSB) Terrence Donnelly Centre for Cellular and Biomolecular Research (CCBR) How can we help you?

2. http://www.medresearch.utoronto.ca/dcm_home.html http://www.medresearch.utoronto.ca/dcm_home.html http://www.research.utoronto.ca/ethics/ea_app.html

3. Contact Information, Order Desk, Short Course Registration, Account Information Animal Care Committee Information, Meeting dates, Deadlines and Animal Use Protocol submission information Animal Care Charges Standard Operating Procedures

4. VETERINARY ASSISTANCE Study Design Animal Models Anesthesia and Analgesia Technical Information ie. Surgical information, blood collection and volumes etc Post Mortem Examination and Histopathology

5. Animal Use Protocol Review

6. Training “Short Course on Animal Care”

7. Mouse Importation and Quarantine

8. Technical Services “Rent a Tech”

9. The Toronto Centre for Phenogenomics

10. The Toronto Centre for Phenogenomics (TCP) TCP Transgenic Core & Specialty Resources –Transgenic and gene knockout services –Available to TCP investigators, University of Toronto Faculty of Medicine, and strategic industrial partners outside TCP –Embryo dissection, culture, and microscopy –Tissue culture and molecular biology laboratories and services –Re-derivation of mouse lines for import to the TCP –Transgenic production by pronuclear microinjection –Generation of chimeras by blastocyst microinjection, morola aggregation, or tetraploid complementation assay –Timed pregnancy services (superovulation, natural mating, pseudopregnancy)

11. Questions and Answers