1. 門診處方討論 報告日期 :93.10.21 報告者 : 王士昇藥師

3. Sulfamethoxazole+Trimethoprim(Baktar) 在後天免疫不全症候群患者之應用 Pneumocystis carinii Pneumonia (PCP) 常發生於 HIV 感染的患者 Baktar 用於預防與治療 Pneumocystis carinii Pneumonia (PCP)

4. Dosage: Children ＞ 2months: Prophylaxis: PO, I.V: 10mg/kg/day TMP and 50mg/kg/day SMZ or 150mg/m2/day TMP and 750/m2/day SMZ Q12H for 3days/week Treatment: IV 20mg/kg/day TMP and 100mg/kg/day SMZ Q6H

5. Adult: Prophylaxis: PO 480mg once daily or 3 times weeks Treatment: PO, IV 15-20mg/kg/day TMP and 75-100mg/kg/day SMZ in 3-4 divided doses

6. Conclusion ： Sulfamethoxazole+Trimethoprim in prophylaxis and treatment pneumocystis carinii pneumonia FDA approval: Adult. Efficacy: Adult, effctive.

7. Reference: 1. Micromedex 2. Drug Information Handbook 11th Edition 3. 2004 常用藥物治療手冊 4.PDR