1. Charmaine J. Palafox, MD

2. Approx. 50% of CHD deaths occurs as sudden cardiac arrest

3. SUDDEN CARDIAC DEATH (SCD)  In the US, SCD is estimated at 300,000 to 350,000 annually  overall incidence is between 1-2 deaths per 1000 persons among the general population Braunwald’s 9 th ed, p 846.

4. PRIMARY PREVENTION FOR SCD  prevention of an initial event among patients at high risk because of an advanced heart disease with low ejection fraction Braunwald’s 9 th ed, p 875.

5. LV Ejection Fraction NEJM, 1983.

6. Europace, 2010:12, p. 1566.

7. Total Mortality Europace, 2010:12, p. 1568.

8. Heart Rhythm, Vol 7, No 7, July 2010, p. 880.

9. NEJM. 2008;359:10, p 1006.

10. J. Am. Coll. Cardiol. 2008;51;e1-e62