1. RAP Retinal angiomatous proliferation Edi LadavacGeneral Hospital Pula

2. Drusen Atrophic type Exudative form AMD

3. Exudative AMD CNV Disciform scar Choroidal-retinal anastomosis

4. Exudative AMD = CNV ? ? ?

5. Exudative AMD Yannuzzi (2001) 1.choroidal neovascularisation ( CNV) 2.retinal angiomatous proliferation (RAP) 3.polypoidal choroidal neovascularisation NEW !

6. RAP White patientsWhite patients bilateralbilateral Dg. FAG + ICGA + OCTDg. FAG + ICGA + OCT therapytherapy

7. RAP – clinical picture IRN Stage I - IRN (intraretinal neovascularisation) SRN Stage II - SRN (subretinal neovascularisation) CNV Stage III - CNV (choriodal neovascularisation)

8. RAP – stage I Intraretinal angiomatous proliferationIntraretinal angiomatous proliferation RRA (retinal-retinal anastomosis)RRA (retinal-retinal anastomosis) HemorrhagesHemorrhages

9. RAP – stage II elevation retinal elevation reaction of the RPEa reaction of the RPEa PED PED

10. RAP stage III Choroidal neovascularisation (CNV)Choroidal neovascularisation (CNV) Retinal-choroidal anastomosis (RCA)Retinal-choroidal anastomosis (RCA)

11. RAP- diagnosis Biomicroscopic examinationBiomicroscopic examination FAGFAG ICGAICGA OCTOCT

12. RAP – case report Small hemorrhagesSmall hemorrhages Case I Case II

13. RAP –case report Feeding arteriole (dilated vessels)Feeding arteriole (dilated vessels) Case I Case II

14. RAP - case report Retinal oedemaRetinal oedema PEDPED Case I Case II

15. RAP – case report ICG angiographyICG angiography Case I Case II Trieste – Padova 2004

16. RAP - therapy 1.PDT + triamcinolone intravitreal 2.VEGF inhibitors (Macugen) intravitreal 3.Macular surgery 4.Laser

17. RAP - therapy Triamcinolone + PDTTriamcinolone + PDT Before th After th Trieste - 2004 OCT

18. RAP - conclusion CNV AMD RAP PCN Exudative form

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