1. Cognitive Testing of HPV Vaccine Survey Items Noel Brewer, UNC School of Public Health and the HPV Cognitive Testing Workgroup

2. 2 Purpose Solicit feedback on study design Describe process for inviting participation in project

3. Motivation for Study Strong interest in topic  70+ studies of HPV vaccine acceptability and uptake Measurement issues  No standardized measures  Little published work on item evaluation Interest and expertise in CPCRN

4. Cognitive Testing  Protocol for structured interview  Participant answers several survey items  Interviewer engages participant in conversation that explores the meaning of the items and their answers

5. Study Scope HPV vaccination to prevent cervical cancer Parents of adolescent girls  72-90 interviews  English (+ other languages, if sites have capacity and time allows) Race/ethnicity (Black, Hispanic, White, Asian?) Expedited IRB approval

6. Tasks UNC coordinating center  Draft protocol  Draft IRB application  Telephone training of interviewers  Coordinate participant incentives  Draft manuscript Data collection centers (3-4 proposed)  Revise and file IRB application  Designate interview staff  Collect data from 10-20 parents of adolescents  If non-English survey, translation of items Participating centers  Analyze data All centers participate in study phone meetings and approve protocol

7. Proposed Timeline 2008 10/15Decision by sites about participation 11/1Draft interview protocol 12/1File IRB applications 1/1Finalize survey instrument 2009 1/15Interviewer training 5/1Complete interviews 7/1Analyze findings 9/1Manuscript submitted