1. Combining Vital Signs and Laboratory Data in an Early Warning Score Stuart Jarvis

2. National Early Warning Score Based on vital signs measurements 3210123 Resp. Rate (/min) ≤89–11 12–2021–24≥25 SpO 2 (%) ≤9192–9394–95≥96 Supplemental O 2 YesNo Temperature (°C) ≤35.0 35.1-36.036.1–38.038.1–39.0 ≥39.1 Systolic BP (mmHg) ≤9091–100101–110111–219≥220 Heart rate (/min) ≤4041–5051–9091–110111–130≥131 Conscious level AlertNot alert

3. Lab Measurement selection haemoglobin white cell count urea creatinine sodium potassium albumin

4. A Lab EWS: LDT-EWS MALE3210123 Hb≤11.111.2-12.8≥12.9 WCC≤9.39.4-16.6≥16.7 U≤9.49.5-13.7≥13.8 Cr≤114115-179≥180 Na≤132133-140≥141 K≤3.73.8-4.44.5-4.7≥4.8 Alb≤3031-34≥35

5. A Lab EWS: LDT-EWS FEMALE3210123 Hb≤12.012.1-14.8≥14.9 WCC≤12.612.7-14.8≥14.9 U≤8.48.5-13.8≥13.9 Cr≤9192-157≥158 Na≤134135-140≥141 K≤3.33.4-4.5≥4.6 Alb≤2829-34≥35

6. Performance

8. Summary Laboratory based EWS (LDT-EWS) can discriminate final outcome LDT-EWS discriminates final outcome better than NEWS Combining LDT-EWS and NEWS offers best discrimination of final outcome