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Ensemble Synchronization in Schizophrenia Kaushik Majumdar, ISI Bangalore Joint work with Pradeep D. Prasad (ISI), John P John (NIMHANS), H. N. Harsha (Nitte University) https://sites.google.com/site/isicng/ (Computational Neuroscience Group) Electrical Geodesics Inc & Neuroinformatics Center, UO, 15 Nov. 2013
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Video Synchronization: Snapshot
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Pairwise Hilbert Phase Synchronization Prasad et al. Clin. EEG Neurosci. 44(1): 16 – 24, 2013
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Hilbert Transformation and Instantaneous Phase
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Phase Synchronization Prasad et al. 2012
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Cross Modal Task
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Videos Healthy control subject http://youtu.be/4aFMQFhiRHw http://youtu.be/4aFMQFhiRHw Patient with schizophrenia http://youtu.be/-TECG5XQhB4 http://youtu.be/-TECG5XQhB4
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Multi-channel synchronization
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Single Trial Ensemble Synchronization
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Trial Averaged Ensemble Synchronization
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ERSP & ITC
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Trial Selection
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Classification by Logistic Regression 3 dimensional feature space: 1.Ensemble right hemispheric synchronization. 2.Ensemble left hemispheric synchronization. 3.Response latency.
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2 Dimensional Projection of 3 Dimensional Feature Space Cross is patient with schizophrenia square is healthy control subject Incongruent stimulus
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2 Dimensional Projection of 3 Dimensional Feature Space Congruent stimulus Plus is patient with schizophrenia circle is healthy control subject
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2 Dimensional Projection of 3 Dimensional Feature Space Neutral stimulus Star is patient with schizophrenia diamond is healthy control subject
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Average Accuracy
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Probabilistic Score
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Reference P. D. Prasad, H. N. Halahalli, J. P. John and K. Majumdar, “Single-trial EEG classification using logistic regression based on ensemble synchronization,” accepted in IEEE Journal on Biomedical and Health Informatics.
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