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DYSPNEA Menaldi Rasmin
Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, University of Indonesia Persahabatan Hospital, Jakarta
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INTRODUCTION Dyspnea: Discomfort feeling in breathing
Subjective and difficult to measure Etiology : lung, heart, endocrine, kidney, neurology, hematology, rheumatology and psichology Prevalence of dyspnea → no accurate data 1
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VENTILATORY REGULATION
Ventilatory Central Centre located in the medulla of the brainstem composed of several subcenters, that interact to produce rhytmical breathing output is transmitted to phrenic nerves to diaphragm and respiratory muscles affected by Higher cortical centers Mechanical Chemical stimuli
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Cortical Centers Mechanical reflexes input to the ventilatory center
result; breathing partially under voluntary control Mechanical reflexes emanate from skeletal muscle spindle pulmonary vessels and tissue
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Dyspnea breathlessness shortness of breath
uncomfortable or unpleasant respiratory-related sensation not tachypnea, not hyperpnea and not hyperventilation but; difficult, labored, uncomfortable breathing; it is unpleasant type of breathing though not painful in the usual sense of the word. It is subjective and, like pain, it involves both perception of the sensation by the patient and his reaction to the sensation Comroe (1966)
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“ an uncomfortable awareness of breathing or an increased respiratory effort that is unpleasant and regarded as in appropriate” (Mahler et al 1984)
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DEFINITION OF DYSPNEA The American Thoracic Society (ATS):
the term of discomfort perception subjective in breathing that consist of sensation with different intensity as a results of interaction of various physiologic, social and environtmental factors. 3
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MECHANISM OF DYSPNEA Interaction between signal and receptor in otonomic nerve system, motoric cortex,airway receptor, lung and thoracic cage →dyspnea 4
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MECHANISM OF DYSPNEA Dyspnea Emosi Komplek pernapasan
Dispnea Komplek pernapasan Paru & dinding dada kognitif perilaku Emosi Stimulasi kemoreseptor latihan Kortek motorik primer Kortek sensorik primer MECHANISM OF DYSPNEA Dyspnea Complex of breathing Lung and thoracic cage Cognitive Behavior Emotion Chemoreceptor stimulation Exercise Primary motoric cortex Primary sensoric corte
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MECHANISM OF DYSPNEA
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MEASUREMENT OF DYSPNEA
Aim : to differentiate the severity and to evaluate the nature of dyspnea Technique of measurement : visual analogue scale Borg scale Medical Research Council (MRC) Dyspnea Scale American Thoracic Sosiety (ATS) Dyspnea Scale Baseline Dyspnea Index (BDI) Transitional Dyspnea Index (TDI)
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ATS dyspnea index Grade 1 : No dyspnea except severe exercise activity
Grade 2 : Dyspnea when climb the step in hurry or climb a small hill Grade 3 : Walk slower compared to common people Grade 4 : Must stop for breathing after 100 yard walk Grade 5 : Dyspnea while put on / off the clothes
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pulmonary non-pulmonary
Dyspnea pulmonary non-pulmonary (cardiac) *pulm edema *arrhythmias *asthma/COPD *acute MI *PE *myocardial ischemia *pneumonia *pneumothorax
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DYSPNEA IN PULMONARY DISEASE
Abnormality of breathing mechanism, lung become more stiff, weakness of ventilation muscles. Restrictive lung diseases. Obstructive lung diseases. Disturbance of lung diffusion. Disturbance of lung perfusion.
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RESTRICTIVE LUNG DISEASE
Lung : - atelectasis - fibrosis - lung tumour - bullae - lung abscess Mediastinum : - mediastinal tumour - cardiomegali - pericardial effusion
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ATELECTASIS
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PANCOAST TUMOR
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LUNG ABSCESS
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DESTROYED LUNG
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BULLAE
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BULLAE
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RESTRICTIVE LUNG DISEASE
Pleura : - pleural effusion - pleural tumour - pneumothorax Diaphragm : - hernia of diaphragm - paralize of diaphragm Bone : - rib fracture - pectus excavatum - scoliosis, kyphosis Muscle : - myasthenia gravis
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PLEURAL EFUSSION
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PNEUMOTHORAX
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HYDROPNEUMOTHORAX
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OBSTRUCTIVE LUNG DISEASE
Asthma COPD : - Chronic bronchitis - Emphysema Bronchiectasis Lung tumour Foreign body
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BRONCHIECTASIS
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LUNG TUMOR
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DISTURBANCE OF DIFFUSION
Alveolar wall Interstitial space Arterial wall Plasma Red blood cell wall
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PNEUMONIA
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ARDS
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DISTURBANCE OF PERFUSSION
Pulmonary emboli Congestive heart failure
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LUNG NODULES
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MILLIARY TB
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CONCLUSION Dyspnea is a subjective symptom
Various abnormalities may cause dyspnea Severity of dyspnea can be measured
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Thank You
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