2. CREATIONPOOL OF EXPERTS INDUSTRY LINK BIO-TECHNOLOGYOUTSOURCINGSERVICESPRODUCTSPARTNERSHIP CREATIONPOOL OF EXPERTS INDUSTRY LINK BIO-TECHNOLOGYOUTSOURCINGSERVICESPRODUCTSPARTNERSHIP

3. CREATIONPOOL OF EXPERTS INDUSTRY LINK BIO-TECHNOLOGYOUTSOURCINGSERVICESPRODUCTSPARTNERSHIP Business to Business services A proven track record and lots of experience in the development of microelectronic systems for biomedical applications –Design and development of microsystems and microelectronics –Electronics system development –Custom packaging development –Firmware development –Prototyping / Testing –Consulting

4. CREATIONPOOL OF EXPERTS INDUSTRY LINK BIO-TECHNOLOGYOUTSOURCINGSERVICESPRODUCTSPARTNERSHIP A technology......A complete system BASIC RESEARCH APPLIED RESEARCH EXPERIMENTAL PROTOTYPE PRE-INDUSTRIAL PROTOTYPE INDUSTRIAL PROTOTYPE PRODUCT MANUFACTURE DISTRIBUTION CUSTOMER SERVICES SERVICES

5. CREATIONPOOL OF EXPERTS INDUSTRY LINK BIO-TECHNOLOGYOUTSOURCINGSERVICESPRODUCTSPARTNERSHIP Accessibility to Biomedical Applications Electronic System Development Custom Design Microelectronic Design Microsystem Development Firmware High-level Software Biocompatible Lead Development Packaging for Implantable Devices Prototyping/testing Consulting

6. CREATIONPOOL OF EXPERTS INDUSTRY LINK BIO-TECHNOLOGYOUTSOURCINGSERVICESPRODUCTSPARTNERSHIP Neural stimulator Sacral root stimulator –All the way from the lab prototype to the pre- industrial prototype –Partners: CCC Instituto Guttman

7. CREATIONPOOL OF EXPERTS INDUSTRY LINK BIO-TECHNOLOGYOUTSOURCINGSERVICESPRODUCTSPARTNERSHIP Chemical sensors

8. CREATIONPOOL OF EXPERTS INDUSTRY LINK BIO-TECHNOLOGYOUTSOURCINGSERVICESPRODUCTSPARTNERSHIP MicroCard © impedance sensors

9. CREATIONPOOL OF EXPERTS INDUSTRY LINK BIO-TECHNOLOGYOUTSOURCINGSERVICESPRODUCTSPARTNERSHIP Cool-Box device

10. CREATIONPOOL OF EXPERTS INDUSTRY LINK BIO-TECHNOLOGYOUTSOURCINGSERVICESPRODUCTSPARTNERSHIP Bluetooth based telemetry module

11. CREATIONPOOL OF EXPERTS INDUSTRY LINK BIO-TECHNOLOGYOUTSOURCINGSERVICESPRODUCTSPARTNERSHIP INTEGRATION Technology Software Electronics Multidisciplinarity State Machine Sensor1Telemetry StimSensor2

12. CREATIONPOOL OF EXPERTS INDUSTRY LINK BIO-TECHNOLOGYOUTSOURCINGSERVICESPRODUCTSPARTNERSHIP Accelerating Product Development Economy in Time and Costs and high Quality Products 0 1 2 3 4 5 6 7 8 9 10 Better CAD Using proven manufact. processes Working with hospital partner Engineering re-use Mfr FDA Trials Production Prototyping Feasability Concept

13. CREATIONPOOL OF EXPERTS INDUSTRY LINK BIO-TECHNOLOGYOUTSOURCINGSERVICESPRODUCTSPARTNERSHIP Access to facilities & experts Universities Research centers Networks Industries i2m Prototyping Pre-serie Clean roomDesign facilities

14. CREATIONPOOL OF EXPERTS INDUSTRY LINK BIO-TECHNOLOGYOUTSOURCINGSERVICESPRODUCTSPARTNERSHIP Reference Cases Neurostream (Canada) Biocontrol (Israel) CVRx (US) Illini Group (US) Biosystems (Spain) Poitier Hospital (France) AMC (Nederland's) CSC (Spain) FCI (Colombia) Guttman (Spain) Carburos metalicos (Spain)

15. CREATIONPOOL OF EXPERTS INDUSTRY LINK BIO-TECHNOLOGYOUTSOURCINGSERVICESPRODUCTSPARTNERSHIP Actual Prototype (i) Activity Cardiac Pulse Respiratory Rate Spirometry Blood Pressure ECG SPO2 Base Unit Portable Unit

16. CREATIONPOOL OF EXPERTS INDUSTRY LINK BIO-TECHNOLOGYOUTSOURCINGSERVICESPRODUCTSPARTNERSHIP Actual prototype (ii)

17. CREATIONPOOL OF EXPERTS INDUSTRY LINK BIO-TECHNOLOGYOUTSOURCINGSERVICESPRODUCTSPARTNERSHIP Softwares

18. CREATIONPOOL OF EXPERTS INDUSTRY LINK BIO-TECHNOLOGYOUTSOURCINGSERVICESPRODUCTSPARTNERSHIP I2m offer : alternative 1 Vital parameters Based on the actual prototype Includes –Pulsooximetry –ECG –Temperature –Skin humidity –Activity

19. CREATIONPOOL OF EXPERTS INDUSTRY LINK BIO-TECHNOLOGYOUTSOURCINGSERVICESPRODUCTSPARTNERSHIP Contact person Aliette Mouroux Edificio CNM | Campus U.A.B. 08193 Bellaterra | Barcelona | Spain T + 34 93 594 77 00 | F +34 93 580 14 96 info@i2m-design.com www.i2m-design.com

20. CREATIONPOOL OF EXPERTS INDUSTRY LINK BIO-TECHNOLOGYOUTSOURCINGSERVICESPRODUCTSPARTNERSHIP