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Published byGavin Porter Modified over 9 years ago
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Choroidal Tuberculoma Rupesh Agrawal, Carlos Pavesio Moorfields Eye Hospital, NHS Foundation Trust, London, United Kingdom
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Ocular History 48 year Female OD: complaints of decreased vision for few months previously bilateral acute angle closure, bilateral intermediate and posterior uveitis 4 months prior to consultation by our team (per referral)
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First Presentation - Ocular Examination Visual acuity OD: 6/60 OS: 6/6 AC- 1+ cells lens clear anterior vitreous 1+ cells
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First Presentation - Fundus OD choroidal tuberculoma temporal to fovea
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First Presentation - FFA OD blocked areas of hypofluorescence with stippled late hyperfluorescence
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First Presentation - FFA OD blocked areas of hypofluorescence with late hyperfluorescence
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First Presentation - FFA OS stippled hyperfluorescent lesions and no increase in size and extent of the lesion
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First Presentation - ICGA OU: hypocyanescent lesions
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First Presentation - Investigations CBC, U/E, LFT’s - normal ACE, syphilis -negative QuantiFERON gold - awaited Chest X-ray - normal
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First Diagnosis Choroiditis of unclear origin based on clinical findings
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Treatment Prednisolone 70mg/day x 1 week
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Follow-up – After 1 Week QuantiFERON Gold +ve QuantiFERON Gold +ve urgent chest physician appointment urgent chest physician appointment
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New Diagnosis Ocular Tuberculosis related choroidal granuloma based on clinical findings positive QuantiFERON testing
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New Treatment anti tubercular therapy started: 4 drug regime x 2 months followed by 2 drugs for 10 months anti tubercular therapy started: 4 drug regime x 2 months followed by 2 drugs for 10 months quick corticosteroid taper quick corticosteroid taper
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Follow-up – After 3 Weeks resolution of choroiditis lesions
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Follow up – After 1 Month patient started on anti-tubercular therapy new granuloma in the left eye continued prednisolone at 40mg/day dose along with ATT
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Follow-up – After 2 Months OU: resolution of choroidal lesions
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Final Visit ATT with corticosteroids – 12 months Rapid response to ATT Concurrent oral steroid therapy to achieve complete remission Final VA: 20/20 - OU
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