1. Reaxys Demonstration Search Chemistry 137 – Spring 2013 Grace Baysinger Head Librarian & Bibliographer, Swain Chemistry & Chemical Engineering Library graceb@stanford.edu

2. Reaxys – Home Page There are three tabs for searching. Chose Substances and Properties.

3. Reaxys – Generate Structure from Name Click on Generate structure from name button. Then enter name in popup box.

4. Reaxys – Found Chemical Structures If more than one structure is retrieved, choose one that best matches your needs.

5. Reaxys – Substructure Search of Vancomycin Do substructure search, include tautomers and ignore stereo

6. Reaxys – Initial Search Results Summary of available information for each structure Filters for refining search results

7. Reaxys – Filter by Bioactivity – Limit to Substances with Pharmacological Data

8. There are 3,747 articles/patents that have bioactivity on Vancomycin

9. Reaxys – Limit to Articles/Patents Published in 2009-2010

10. Reaxys – Citations Display Form for Reviewing Results View results in Citations format to see titles of articles of potential interest

11. Reaxys – Output Results Click on Output choice to create PDF of search results

12. Reaxys – Popup Window Choices for Specifying Output Format

13. Reaxys – Output Citation Results

14. Reaxys – Record from Output that includes Hit Substance, Citation, and Abstract for Reference with Bioactivity Information View in Reaxys hot link lets you go to substance record for that compound from PDF

15. Reaxys – Online Training at http://info.reaxys.com Training center includes Quick Reference Guide