1. Question of the DAY Jan 14 During DNA Replication, a template strand is also known as a During DNA Replication, a template strand is also known as a A. complementary strand A. complementary strand B. copied strand B. copied strand C. sister strand C. sister strand D. parent strand D. parent strand

2. AGENDA Jan 14 Objective: Compare the structure and function of DNA to RNA Objective: Compare the structure and function of DNA to RNA 1. Question of the Day 1. Question of the Day 2. PART 2 of Chapter 12 2. PART 2 of Chapter 12 12-3 RNA 12-3 RNA Creating your Code Activity Creating your Code Activity 3. Homework and Review 3. Homework and Review 12-3 Guided Reading Packet 12-3 Guided Reading Packet Complete Creating your Code Activity Complete Creating your Code Activity

3. 12-3: RNA decodes the genetic information in DNA decodes the genetic information in DNA nucleic acid nucleic acid differs from DNA in 3 ways differs from DNA in 3 ways sugar is ribose sugar is ribose single-stranded single-stranded contains uracil (U) instead of thymine contains uracil (U) instead of thymine

4. Transcription process by which mRNA molecules are made process by which mRNA molecules are made DNA is the template for mRNA DNA is the template for mRNA DNA can be copied in Replication DNA can be copied in Replication DNA can produce mRNA in Transcription DNA can produce mRNA in Transcription

5. Transcription RNA polymerase: an enzyme that binds directly to a molecule of DNA RNA polymerase: an enzyme that binds directly to a molecule of DNA produces a strand of RNA produces a strand of RNA AACT  UUGA AACT  UUGA begins and stops transcription at special start and stop sequences on the DNA begins and stops transcription at special start and stop sequences on the DNA

6. Transcription Practice 1. Copy the following strand of DNA… 1. Copy the following strand of DNA… A T T G G C T C C A T G C A T T G G C T C C A T G C 2. Transcribe your copied strand from #1. 2. Transcribe your copied strand from #1.

7. Practice Problem Replication Replication 1. A T T G G C T C C A T G C 1. A T T G G C T C C A T G C T A A C C G A G G T A C G T A A C C G A G G T A C G Transcription Transcription 2. T A A C C G A G G T A C G 2. T A A C C G A G G T A C G A U U G G C U C C A U G C A U U G G C U C C A U G C

9. DO NOW Jan 15 1. HOMEWORK CHECK and REVIEW 1. HOMEWORK CHECK and REVIEW 2. Complete Creating your Code Activity 2. Complete Creating your Code Activity

10. AGENDA Jan 15 Objective: Explain the function of each type of RNA. 1. DO NOW 1. DO NOW 2. Types of RNA and genetic code 2. Types of RNA and genetic code 3. CODON CHART 3. CODON CHART 4. Homework and Review 4. Homework and Review

11. Forms of RNA mRNA: messenger RNA mRNA: messenger RNA carries copies of instructions for the assembly of amino acids into polypeptides carries copies of instructions for the assembly of amino acids into polypeptides rRNA: ribosomal RNA rRNA: ribosomal RNA Found in ribosomes Found in ribosomes WHAT do ribosomes do? WHAT do ribosomes do? tRNA: transfer RNA transfers amino acids to assemble a protein tRNA: transfer RNA transfers amino acids to assemble a protein

12. Genes in Pieces mRNA is edited mRNA is edited Introns are parts that are not used Introns are parts that are not used exons: remaining parts spliced together. exons: remaining parts spliced together. are expressed are expressed

13. Genetic Code amino acids  polypeptides  proteins amino acids  polypeptides  proteins order of amino acids determine protein order of amino acids determine protein instructions in DNA that determine the assembly of a protein. instructions in DNA that determine the assembly of a protein. genetic code genetic code

14. Decoding the Genetic Code nucleotides code for 20 different amino acids nucleotides code for 20 different amino acids Codons – three nucleotides that specify a specific amino acid Codons – three nucleotides that specify a specific amino acid mRNA sequence  AAACACGGU mRNA sequence  AAACACGGU read as 3 codons  AAA-CAC-GGU read as 3 codons  AAA-CAC-GGU Each codon  Each codon  amino acid lysine-histidine-glycine amino acid lysine-histidine-glycine