1. HIV in Brazil Daniela Zilio Larentis Infectious Disease Resident at HCPA

2. Population: 191.000.000 (2010) 630.000 living with HIV ( 2009) AIDS: 592.914 (2009) Number of deaths: 217.091 Reported cases/year: 33-35.000

3. Epidemiology (1980-2009) Men/woman ratio: 1,5; Most affected strata between 30-49y, increasing in older than 50 y; – 47,7 % of infected are white ethnicity; – Pregnant woman: 54.218 20-29 y Ministério da Saúde 2010

4. Source of HIV acquisition (1980-2010) - Vertical transmission: 4.181

5. Co-infection HIV/TBC BK performedCoinfection %

6. HAART 1700 euros/year/pacient (2002-2007) with treatment, Universal access since 1996, When start treatment: 1. Symptomatics 2. Asymptomatics - CD4 >500: no ART - CD4 350-500: HCV, HBV, nephropathy, any cancer, VL> 100.000, high risk for CVD, - CD4 <350: ART 3. Pregnancy

7. Brazilian guidline for treatment - NRTI ZDV, 3TC, TDF - ddI, d4T, ABC -NNRTI EFZ, - NVP -PI ATV, LOP/r - DRV, IDV, APV -Rescue therapy: T20, raltegravir, etravirina, maravirock

8. Appointment: - CD4, CV, - Use of HAART, - Side efects of HAART, - Genotyping, - Advices (protect sex, immunization).

9. Thank you for the attention!!