1. SB2a Build DNA using the Nucleotides Type Your Name Here

2. SB2b Build a model of a replication fork consisting of bases from your DNA from the previous slide. Copy and paste any extra free nucleotides from the previous slide. The nucleotides must be in the same order as your original DNA from slide 1

3. Process SB1ab Why is DNA copied to make more DNA and copied to form the new nucleic acid called RNA? Complete the key for the nitrogen bases for your DNA Model Blue = guanine Green = Red = Adenine Purple =

4. The scissors below represent the enzyme called DNA helicase. It is responsible for cutting the DNA molecule in half by breaking the hydrogen bonds between the bases so that transcription can occur. Copy and paste the nucleotides from a previous slide to show how transcription occurs. RNA nucleotides are provided below to build your mRNA strand between the DNA strands using the top DNA strand as a template. The hand should be placed to show how RNA polymerase joins the RNA nucleotides. The DNA nucleotides must be in the same order as your original DNA from slide 1.

5. Copy and paste your new mRNA strand from the previous slide below

6. Process SB1ab What enzyme does the hand represent on slide 7? Where does transcription take place in a cell? Complete the key for the nitrogen bases for your mRNA Model Blue = guanine Green = Red = Adenine Pink =

7. Record the bases from left to right on your new mRNA molecule for just the first 9 bases 1. How are tRNA molecules like chemical tow trucks? 2. Why are there three connectors on the back of the tow truck (tRNA)? DNA base mRNA base letter CodonAmino acid Anticodon tRNA

8. Process SB1ab What process were you simulating by looking up the mRNA letters (codon) to find the amino acids? Where does this process occur in the cell? What form of RNA is responsible for picking up the amino acids from your table to begin building your protein?

9. Conclusion 1: Complete the diagram below using (click and drag) the words provided

10. Conclusion 2: Once the proteins are produced on the ribosomes.... Where do they go to be refined? What organelle picks them up for packaging and distribution? Label Me

11. Conclusion 3: Compare DNA and RNA nucleotides Compare the shape of DNA and RNA Compare the functions of DNA and RNA

12. Applications How is DNA like a filing cabinet (Hint: Read standard SB2b)? Make an analogy between building a house and building a protein. Be sure to include all words provided from the conclusion 1 diagram slide.